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Filtering by: Subject Microsomes -- Effect of chemicals on Advisor Williams, David E. License All rights reserved

Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by dibenzo[a,l]pyrene in the B6 129 mouse model : role of the Aryl Hydrocarbon Receptor

Creator:

Yu, Zhen

Abstract:

Lymphomas and leukemias are the most common cancer in children and young adults and in utero exposure to carcinogens may contribute to the etiology of these cancers. A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), was administered to pregnant mice (15 mg/Kg b.w., gavage) on gestation day 17. Significant mortalities in...

Resource Type:

Dissertation

Full Text:

3-2 Effect of AHR genotype on mortality of offspring born to DBP-treated dams