Index Catalog // ScholarsArchive@OSU

Creator:: Yu, Zhen
Abstract:: The antimutagenic potency of wheat grain and berry extracts was studied in vitro against several heterocyclic amines (HCAs) using the Salmonella mutagenicity assay and the anticarcinogencity of wheat grain was studied in vivo using the rat colonic aberrant crypt focus assay. Wheat bran, which binds HCAs in vitro, as well...
Resource Type:: Masters Thesis
Full Text:: , Dr. George S. Bailey and Dr. Susan Tornquist. I would also like to thank the staff in Dr

Creator:: Oganesian, Aram
Abstract:: There is plenty of evidence from epidemiology studies supporting a link between certain components in the human diet and cancer incidence. It is estimated that 3-4 million annual cases of cancer could be prevented worldwide just by changing dietary habits. In parts of the world where vegetables and fruits constitute...
Resource Type:: Dissertation
Full Text:: contribution in sampling my carcinogenesis experiments. I was fortunate to have Drs. George Bailey, Donald

Creator:: Shilling, Adam D.
Resource Type:: Dissertation
Full Text:: ideas, mentorship and financial support. I also thank Drs. George Bailey, Fredrick Stormshak, Lawrence

Creator:: Katchamart, Sirinmas
Abstract:: Indole-3-carbinol (I3C), the most abundant metabolite of glucobrassicins, is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower. I3C has been shown to have anticarcinogenic activity against many chemical carcinogens in multiple target organs in animal models. However, the anticarcinogenic activity of I3C is considered indirect since...
Resource Type:: Dissertation
Full Text:: and financial support. Thanks to Drs. Donald Reed, George Bailey, Mark Christensen and Wilbert Gamble

Creator:: Tilton, Susan C.
Abstract:: Indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), a primary I3C derivative in vivo, are known chemopreventive agents available as dietary supplements. I3C was found to suppress or enhance tumors in several animal models. Chemoprotection is attributed to the ability of indoles to alter carcinogen metabolism effectively blocking initiation. However, mechanisms for enhancement...
Resource Type:: Dissertation
Full Text:: outside the lab. I would also like to thank Dr. George Bailey for his advice and kind acknowledgements

Creator:: Yu, Zhen
Abstract:: Lymphomas and leukemias are the most common cancer in children and young adults and in utero exposure to carcinogens may contribute to the etiology of these cancers. A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), was administered to pregnant mice (15 mg/Kg b.w., gavage) on gestation day 17. Significant mortalities in...
Resource Type:: Dissertation
Full Text:: thank Dr. George S. Bailey, Dr. Roderick H. Dashwood, Dr. Ronald E. Wrolstad and Dr. Susan J. Tornquist

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