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Filtering by: Advisor Wong, Weng Keen Subject Bioinformatics

Prediction of gene transcription start sites and initiation patterns from DNA sequence content

Creator:

Morton, Taj H.

Abstract:

The computational identification of gene Transcription Start Sites (TSSs) can provide insights into the regulation and function of genes without performing expensive experiments, particularly in organisms with incomplete annotations. High-resolution general-purpose TSS prediction remains a challenging problem, with little recent progress on the identification and differentiation of TSSs which are...

Resource Type:

Masters Thesis
Algorithms for massive biological datasets

Creator:

Bryant, Douglas W. (Douglas Wesley)

Abstract:

Within the past several years the technology of high-throughput sequencing has transformed the study of biology by offering unprecedented access to life's fundamental building block, DNA. With this transformation's potential a host of brand-new challenges have emerged, many of which lend themselves to being solved through computational methods. From de...

Resource Type:

Dissertation