This dissertation delves into understanding, characterizing, and addressing dataset shift in deep learning, a pervasive issue for deployed machine learning systems. Integral aspects of the problem are examined: We start with the use of counterfactual explanations in order to characterize the behavior of deep reinforcement learning agents in visual input...
Within the past several years the technology of high-throughput sequencing has transformed the study of biology by offering unprecedented access to life's fundamental building block, DNA. With this transformation's potential a host of brand-new challenges have emerged, many of which lend themselves to being solved through computational methods. From de...