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Filtering by: Advisor Zhang, Dahong Subject Cytokinesis

Dissecting the cytoskeletal interaction during cytokinesis and the role of myosin II motors on homologous chromosomes

Creator:

Tseng, Kuo-Fu

Abstract:

Prior to cell cleavage, cytokinetic proteins are recruited into the nascent actomyosin contractile ring. Interactions between spindle microtubules and the cell cortex play a critical role in this recruitment. However, direct evidence for physical interaction between microtubules and the cortex has been lacking. Here we reveal the physical connection between...

Resource Type:

Dissertation
Dissecting induction of cell cleavage

Creator:

Alsop, G. Bradley

Abstract:

Cytokinesis separates replicated chromosomes and cytoplasm into two daughter cells. In animal cells, this is achieved by the formation of a cleavage furrow that bisects the mitotic (or meiotic) spindle. It is known that the mitotic apparatus defines the cell cleavage plane. However, it is not clear how the mitotic...

Resource Type:

Dissertation