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Filtering by: Contributor advisor sim Field, Jennifer Degree Name Master of Science (M.S.)

Determination of ethyl glucuronide and ethyl sulfate as human biomarkers of alcohol exposure in urine by liquid chromatography/electrospray tandem mass spectrometry with large volume injection

Creator:

Hu, Yan

Abstract:

This research was undertaken to develop a sensitive, selective, and rapid analytical method to measure ethyl glucuronide (EtG) and ethyl sulfate (EtS) in urine as urinary biomarkers of alcohol exposure. Large-volume injection (LVI) coupled with liquid chromatography / electrospray tandem mass spectrometry was used to eliminate the need for either...

Resource Type:

Masters Thesis
Large volume (1,800 µL) injection HPLC/MS/MS for the quantitative determination of illicit drugs and human urinary biomarkers in municipal wastewater

Creator:

Chiaia Hernandez, Aurea C.

Abstract:

A sensitive, selective, rapid analytical method based on large-volume injection (LVI) liquid chromatography/ tandem mass spectrometry was developed using commercially-available hardware that eliminates the need for either off-line or on-line solid phase extraction. Centrifugation followed by the direct injection of 1,800 µL was used for the quantification of illicit drugs,...

Resource Type:

Masters Thesis