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Natural products from temperate and tropical marine algae

Creator:: Graber, Melodie A.
Resource Type:: Masters Thesis

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: , 2493-2497. (b) Moore, B. M., II; Seaman, F. C.; Wheelhouse, R. T.; Hurley, L. H. J. Am. Chem. Soc. 1998

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Creator:: Han, Bingnan
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
Resource Type:: Dissertation

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Creator:: Vulpanovici, Florina Alexandra
Abstract:: This thesis details investigations of marine cyanobacterial secondary metabolism, with emphasis on a strain of Phormidium sp. collected in Indonesia. These studies assessed the effects of nineteen putative elicitor compounds on the growth and metabolite production of five species of marine cyanobacteria, biosynthetic investigation of an intriguing secondary metabolite, phormidolide,...
Resource Type:: Dissertation
Full Text:: (Moore, 1999; Kerr, 2000). Thus, extreme care 22 should be taken in the attempt to extrapolate

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Creator:: Sitachitta, Namthip
Abstract:: The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
Resource Type:: Dissertation
Full Text:: unique cyanobacterial metabolites have also been targets for biosynthetic studies. Moore and

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Creator:: Williamson, R. Thomas
Resource Type:: Dissertation
Full Text:: this report, Moore and Seng were able to show the origin of all the carbons in the salinamide class of

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Creator:: Marquez, Brian L.
Abstract:: This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
Resource Type:: Dissertation
Full Text:: secondary metabolites. The pioneering work initiated, and continued, by Dr. Richard Moore of the University

Novel oxylipins and other bioactive metabolites from marine algae

Creator:: Nagle, Dale George
Abstract:: I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
Resource Type:: Dissertation

The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

Creator:: Lopez, Albert
Abstract:: The sea offers a wide variety of potentially useful resources. Marine algae have been a rich source of structurally unique natural products showing diverse biological properties. The current need to develop new antifungal, antibiotic, anticancer and antiviral drugs has prompted intense research efforts into the discovery, isolation and structure determination...
Resource Type:: Masters Thesis

Bioactive natural products from marine algae

Creator:: Tan, Lik Tong
Abstract:: This thesis is an account of my investigation on the natural products deriving from various marine algae and has resulted in the discovery of thirteen novel bioactive metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D...
Resource Type:: Dissertation
Full Text:: important source of pharmaceuticals. Since the pioneering work of Professor Richard Moore in Hawaii, many

ScholarsArchive@OSU

Natural products from temperate and tropical marine algae

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Novel oxylipins and other bioactive metabolites from marine algae

The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

Bioactive natural products from marine algae

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