Index Catalog // ScholarsArchive@OSU

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Creator:: Ramaswamy, Aishwarya V.
Abstract:: Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
Resource Type:: Dissertation
Full Text:: enabled these organisms to survive in predator-rich tropical reef ecosystems. Richard Moore at the

New bioactive natural products from marine algae and cyanobacteria

Creator:: Sabry, Omar Mohamed
Abstract:: This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Resource Type:: Dissertation
Full Text:: Chemother. Pharmacol. 1999, 44, 312-318 29. Luesch, H.; Moore, R. E.; Paul, V. J.; Mooberry, S. L.; Corbett

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Creator:: Williamson, R. Thomas
Resource Type:: Dissertation
Full Text:: this report, Moore and Seng were able to show the origin of all the carbons in the salinamide class of

Natural products from temperate and tropical marine algae

Creator:: Graber, Melodie A.
Resource Type:: Masters Thesis

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: , H.; Moore, R. E.; Paul, V. J.; Mooberry, S. L.; Corbett, 1. H. J. Nat. Prod. 2001, 64, 907-910. 35

The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

Creator:: Lopez, Albert
Abstract:: The sea offers a wide variety of potentially useful resources. Marine algae have been a rich source of structurally unique natural products showing diverse biological properties. The current need to develop new antifungal, antibiotic, anticancer and antiviral drugs has prompted intense research efforts into the discovery, isolation and structure determination...
Resource Type:: Masters Thesis

Natural products from tropical and temperate marine algae

Creator:: Bernart, Matthew W.
Abstract:: Following surveys of seaweeds in Oregon and the Caribbean, four algal species were selected for study on the basis of their crude extract biological activity or thin-layer chromatographic characteristics. Extracts were fractionated by normal phase chromatography, including high performance liquid chromatography (HPLC). Derivatives (methyl esters, acetates, and benzoates) of natural...
Resource Type:: Dissertation

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Creator:: Han, Bingnan
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
Resource Type:: Dissertation

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Creator:: Vulpanovici, Florina Alexandra
Abstract:: This thesis details investigations of marine cyanobacterial secondary metabolism, with emphasis on a strain of Phormidium sp. collected in Indonesia. These studies assessed the effects of nineteen putative elicitor compounds on the growth and metabolite production of five species of marine cyanobacteria, biosynthetic investigation of an intriguing secondary metabolite, phormidolide,...
Resource Type:: Dissertation
Full Text:: . Ann. N. Y. Acad. Sci. 284, 351-357 Luesch, H., Moore, R. E., Paul, V. J., Mooberry, S. L. and Corbett

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Creator:: Milligan, Kenneth Edward
Abstract:: This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...
Resource Type:: Dissertation
Full Text:: , Paul, V.J., Ed., Comstock Publishing Associates: Ithaca, 1996, pp. 93-117. 19 Cronin, G. and Hay, M.E

ScholarsArchive@OSU

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

New bioactive natural products from marine algae and cyanobacteria

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Natural products from temperate and tropical marine algae

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

Natural products from tropical and temperate marine algae

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

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