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Synthesis and evaluation of PEO-coated materials for microchannel-based hemodialysis

Creator:

Heintz, Keely

Abstract:

The marked increase in surface-to-volume ratio associated with microscale devices for hemodialysis leads to problems with hemocompatibility and blood flow distribution that are more challenging to manage than those encountered at the conventional scale. In this work, stable surface modifications with pendant polyethylene oxide (PEO) chains were produced on polycarbonate...

Resource Type:

Masters Thesis

Full Text:

microscale devices for hemodialysis leads to problems with hemocompatibility and blood flow distribution
The adsorption of human recombinant factor VIII in the presence of the nonionic triblock surfactant Pluronic® F-68 at the air-water interface

Creator:

Alkhatib, Aveen K.

Abstract:

The adsorption behavior of a human recombinant Factor VIII (rFVIII) in the presence of the nonionic, poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock surfactant Pluronic® F-68 was evaluated by dynamic air-water tensiometry. Surface tension kinetics were recorded for F-68 in the absence of protein at concentrations ranging from 0 to 10,000...

Resource Type:

Masters Thesis

Full Text:

kinetics were recorded for F-68 in the absence of protein at concentrations ranging from 0 to 10,000 ppm