Index Catalog // ScholarsArchive@OSU

Adenosine analogs suppress seizures induced by bicuculline methiodide in the rat prepiriform cortex

Creator:: Zhang, Ge
Abstract:: Although considerable experimental evidence suggests that endogenous adenosine may function as a modulator of neuronal activity in the etiology or control of seizures, the neuroanatomical and neurochemical basis for the anticonvulsant actions of adenosine have not been well established. A discrete brain region of possible fundamental importance to epileptogenisis within...
Resource Type:: Masters Thesis
Full Text:: . Thomas F. Murray Although considerable experimental evidence suggests that endogenous adenosine may

Adenosine receptor modulation of seizure susceptibility in rats

Creator:: Szot, Patricia
Abstract:: Adenosine is considered to be a neuromodulator or cotransmitter in the periphery and CNS. This neuromodulatory action of adenosine may be observed as an anticonvulsant effect. Dose-response curves for R-phenylisopropyladenosine (PIA), cyclohexyladenosine (CHA), 2-chloroadenosine (2-ClAdo), Nethylcarboxamidoadenosine (NECA) and S-PIA were generated against PTZ seizure thresholds in the rat. The rank...
Resource Type:: Dissertation
Full Text:: . Abstract approved:. Redacted for Privacy Thomas F. Murray / Adenosine is considered to be a

Regulation of neuronal A₁ adenosine receptors

Creator:: Hettinger, Barbara D.
Resource Type:: Dissertation
Full Text:: Abstract approved: Thomas . Murray Adenosine is a ubiquitous physiological regulator and neuromodulator

Pharmacological characterization of the porcine atrial A₁ adenosine receptor

Creator:: Leid, Mark
Abstract:: Cardiac A₁ adenosine receptors mediate cardioinhibitory properties of adenosine and structural congeners. The objective of these studies was to increase our understanding of molecular processes involved in ligand interactions with receptors mediating cardioinhibitory effects of adenosine and the interactions of these receptors with guanine nucleotide binding regulatory proteins. Porcine atrial...
Resource Type:: Dissertation
Full Text:: Adenosine Receptor Redacted for privacy Abstract approved: Thomas F. Murray / Cardiac Al adenosine

Ontogeny of A₁ adenosine receptor-mediated negative chronotropy in embryonic chick heart

Creator:: Blair, T. Ann
Resource Type:: Dissertation
Full Text:: Negative Chronotropy in Embryonic Chick Heart Abstract approved: Redacted for privacy Thomas F. Murray

Purine nucleotide-induced seizures in rat prepiriform cortex

Creator:: Zhao, Xiaoqin S.
Resource Type:: Masters Thesis
Full Text:: Abstract Approved: Dr. Thoma . Murray ATP has recently been shown to function as a fast neurotransmitter

Development and characterization of a model of glutamate and domoate toxicity in cultured rat cerebellar granule neurons

Creator:: Berman, Frederick W.
Abstract:: A model of acute glutamate- and domoate-induced toxicity was developed and characterized in cultured rat cerebellar granule cells (CGCs) using experimental conditions which preserve the voltage-dependency of NMDA receptor function. Glutamate, which is normally non-toxic to CGCs in physiologic media (pH 7.4), was shown to induce a cytotoxic response after...
Resource Type:: Dissertation
Full Text:: Granule Neurons. Abstract approved: Thomas F. Murray A model of acute glutamate- and domoate-induced

Interaction of dextrorotatory opioids with the N-methyl-D-aspartate receptor

Creator:: Roth, Jane
Resource Type:: Dissertation
Full Text:: support of Professor Thomas F. Murray. I thank Dr. Murray for his guidance, encouragement, friendship

Interactions of pyrethroid insecticides with GABAA and peripheral-type benzodiazepine receptors

Creator:: Devaud, Leslie L.
Resource Type:: Dissertation
Full Text:: PrivacyI Dr. Thomas F. Murray, Associate Prgressor of Pharmacy Dr. R chard OhvaT1, Dean of the College of

Activation of adenosine receptors in prepiriform cortex modulates seizure susceptibility

Creator:: Zhang, Ge, 1956-
Resource Type:: Dissertation
Full Text:: Cortex Modulates Seizure Susceptibility Abstract approved: Thomas F. Murray The objective of these

ScholarsArchive@OSU

Adenosine analogs suppress seizures induced by bicuculline methiodide in the rat prepiriform cortex

Adenosine receptor modulation of seizure susceptibility in rats

Regulation of neuronal A₁ adenosine receptors

Pharmacological characterization of the porcine atrial A₁ adenosine receptor

Ontogeny of A₁ adenosine receptor-mediated negative chronotropy in embryonic chick heart

Purine nucleotide-induced seizures in rat prepiriform cortex

Development and characterization of a model of glutamate and domoate toxicity in cultured rat cerebellar granule neurons

Interaction of dextrorotatory opioids with the N-methyl-D-aspartate receptor

Interactions of pyrethroid insecticides with GABAA and peripheral-type benzodiazepine receptors

Activation of adenosine receptors in prepiriform cortex modulates seizure susceptibility

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