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Filtering by: Contributor advisor sim Perez, Viviana Remove constraint Contributor advisor sim: Perez, Viviana

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Characterizing the accumulation of cellular senescence in the PS19 mouse model

Creator:

Valerio, Juno, Riordan, Ruben, Dimas-Munoz, Jovita, Ross, Grace, Zhen, Yu, Wang, Rong, and Perez, Viviana

Abstract:

Research poster for Summer Undergraduate Research Symposium 2019. Research was conducted with CURE funding in the Perez lab studying cellular senescence in the PS19 mouse model.

Resource Type:

Poster
The Role of Nrf2 in Brain Cellular Senescence

Creator:

Ross, Grace K.

Abstract:

Aging is a major risk factor for the deterioration of biochemical pathways that lead to many chronic neurodegenerative disorders (i.e. Parkinson’s and Alzheimer's Disease). Cellular senescence is a hallmark of aging, a condition characterized by stable growth arrest resulting in a cell that no longer divides, but is metabolically active....

Resource Type:

Honors College Thesis
Identifying the role of autophagy in the protection against protein aggregation

Creator:

Chung, Ryan H

Abstract:

Aging is a process that all living species experiences and it also is greatly to study and understand the aging process with the aim of extending human life span. Protein homeostasis is one of the main hall mark of aging. Based on previous data, it observed that cells from long...

Resource Type:

Poster
The role of Nrf2 in the anti-cell senescence effect of rapamycin

Creator:

Dang, Ivana N.

Resource Type:

Presentation
Comparative analysis of genes regulating HDL function and metabolism in macaques and humans

Creator:

Clarke, Jordyn M.

Abstract:

The role of the high density lipoprotein (HDL) molecule is currently an area of great interest within the scientific community. Previously, mouse and human studies have demonstrated an inverse association between HDL cholesterol (HDL-C) levels and cardiovascular disease. Recent clinical trials, which increased HDL-C, have failed to reduce the number...

Resource Type:

Honors College Thesis
The Effects of Rapamycin on the Unfolded Protein Response in Relation to Healthy Aging

Creator:

Zhao, Stephanie Anne

Abstract:

The loss of proteostasis is the mechanism for maintaining properly folded proteins and degrading misfolded ones. One protective mechanism against loss of proteostasis is the Unfolded Protein Response (UPR), a chaperone mediated folding system in the Endoplasmic Reticulum (ER). The UPR communicates with the Nrf2 pathway, a transcription factor, and...

Resource Type:

Honors College Thesis
Enhanced Protein Homeostasis Mechanisms in Naked Mole Rats Cells

Creator:

Pride, Harrison, Coles, Alex, Mochnick, Jillian, Zhang, Yiqiang, Buffenstein, Rochelle, Hornsby, Peter J., Austad, Steve, Richardson, Arlan, and Perez, Viviana I.

Abstract:

Phylogenic studies suggest that cells from long-lived species are more resistant to a variety of stressors than short-lived species. However, there is little information on the cellular mechanisms that give rise to increased resistance to stress. Our previous studies have shown that liver proteins from a long-lived species have lower...

Resource Type:

Poster

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Academic Affiliation

Biochemistry and Biophysics2
Microbiology1

Advisor

Perez, Viviana7

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 2016 to 2020

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Unknown 2

Committee Member

Magnusson, Kathy1
Van Zee, Kari1

Creator

Austad, Steve1
Buffenstein, Rochelle1
Chung, Ryan H1
Clarke, Jordyn M.1
Coles, Alex1
more Creators »

Contributor

Perez, Viviana1
Wang, Rong1

Date

Date range begin – Date range end

Current results range from 2013 to 2020

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Decade

2020-20291
2010-20196

Degree Field

Biochemistry and Biophysics4
Biochemistry and Molecular Biology1
Biology1

Degree Level

Bachelor's7

Degree Name

Honors Bachelor of Science (H.B.S.)4
Bachelor of Science (B.S.)3

Language

English [eng]7

License

All rights reserved2
Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND 4.0)1

Non-Academic Affiliation

Oregon State University. Undergraduate Research, Scholarship, and the Arts (URSA)4
Oregon State University. Honors College3

Peer Reviewed

No5

Resource Type

Honors College Thesis3
Poster3
Presentation1

Rights Statement

In Copyright5
Copyright Not Evaluated2

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