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Filtering by: Creator Barnett, Morris Committee Member Alani, Adam

Inhalable Lipid Nanoparticles for Messenger RNA Therapeutics

Creator:

Kim, Jeonghwan

Abstract:

Messenger RNA (mRNA) therapy has massive potential to treat various genetic disorders by providing effective proteins to the diseased cells and tissues. Its therapeutic applications include protein replacement, genome editing, and immunotherapy. For successful mRNA treatment, mRNA must be delivered to the cytosol of target cells. One of the leading...

Resource Type:

Dissertation
Investigating Multimodal Therapies with Nanotechnology to Engineer Advanced Chemoradiation Platforms

Creator:

DuRoss, Allison N.

Abstract:

The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...

Resource Type:

Dissertation