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Filtering by: Creator Reiff, Steven D. Remove constraint Creator: Reiff, Steven D. Committee Member Anderson, Kim A. Remove constraint Committee Member: Anderson, Kim A. Degree Field Chemistry Remove constraint Degree Field: Chemistry

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  • Total synthesis of phorboxazole A

    Creator:
    Lee, Tae Hee
    Abstract:
    The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A. The synthesis used a convergent approach involving...
    Resource Type:
    Dissertation
    Full Text:
    : James D. White The total synthesis of a highly potent cytotoxic marine natural product

  • Development of novel analytical methods to detect emerging contaminants in aqueous environmental matrices using large-volume injection

    Creator:
    Backe, Will J.
    Abstract:
    It is the responsibility of humans, as environmental stewards, to monitor our impact on the environment so that efforts can be made to remediate the effects of our actions and change behaviors. To better understand our environmental footprint, sensitive and simple analytical methods are needed to quantify the contaminants that...
    Resource Type:
    Dissertation
    Full Text:
    contaminants. 1.3 Literature Cited (1) Richardson, S. D.; Ternes, T. A., Anal. Chem. 2011, 83, (12), 4614