We are developing a flavin-containing (Fmo) knock-out mouse for Fmo2 that will be utilized to elucidate the role of active human FMO isoform 2 (FMO2.1) in xenobiotic metabolism and toxicity. Since FMO2 is primarily expressed in lung this will provide information on how 27% of African-Americans and 5% of Hispanics...
Temperate evergreen forests of the Pacific Northwest support big huckleberries (Vaccinium membranaceum) despite their nutrient impoverished soils. Acquisition of nitrogen and phosphorous are the major nutrients limiting V. membranaceum. The plant’s access to these resources is linked to their mycorrhizal symbiosis. To learn more about the symbionts of eriaceous plants...