Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Subject Radioisotopes in the body Committee Member Backman, Joseph Creator Wei, Hao

1. The role of copper and its chelation by tetrathiomolybdate in inflammation and atherosclerosis

Creator:: Wei, Hao
Abstract:: Endothelial activation with increased expression of cellular adhesion molecules, chemokines and pro-inflammatory cytokines critically contributes to vascular inflammation and the initiation and progression of atherosclerosis. By affecting redox-sensitive cell signaling pathways and transcription factors, redox-active transition metal ions, such as copper and iron, may play an important role in these...
Resource Type:: Dissertation
Full Text:: ................................................................ 11 1.2.1 Regulation of copper homeostasis in the body ..................................... 12