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Filtering by: Subject Radioisotopes in the body Remove constraint Subject: Radioisotopes in the body Committee Member Backman, Joseph Remove constraint Committee Member: Backman, Joseph

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  • The role of copper and its chelation by tetrathiomolybdate in inflammation and atherosclerosis

    Creator:
    Wei, Hao
    Abstract:
    Endothelial activation with increased expression of cellular adhesion molecules, chemokines and pro-inflammatory cytokines critically contributes to vascular inflammation and the initiation and progression of atherosclerosis. By affecting redox-sensitive cell signaling pathways and transcription factors, redox-active transition metal ions, such as copper and iron, may play an important role in these...
    Resource Type:
    Dissertation
    Full Text:
    ................................................................ 11 1.2.1 Regulation of copper homeostasis in the body ..................................... 12