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Filtering by: Subject Aromatic amines Committee Member Bailey, George S. Subject Antineoplastic agents

Antimutagenic potency of wheat grain and berry extracts in vitro and anticarcinogenicity of wheat grain in vivo

Creator:

Yu, Zhen

Abstract:

The antimutagenic potency of wheat grain and berry extracts was studied in vitro against several heterocyclic amines (HCAs) using the Salmonella mutagenicity assay and the anticarcinogencity of wheat grain was studied in vivo using the rat colonic aberrant crypt focus assay. Wheat bran, which binds HCAs in vitro, as well...

Resource Type:

Masters Thesis

Full Text:

amine group, and subsequently O-acetyltransferase forms a nitrenium ion that interacts with DNA to