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Filtering by: Creator Chavez, Juan Committee Member Barofsky, Doug

Mass spectrometry-based identification and characterization of protein and peptide adducts of lipoxidation-derived aldehydes

Creator:

Chavez, Juan D.

Abstract:

Oxidative stress is recognized as an important underlying factor in the pathogenesis of many degenerative diseases as well as normal senescence. The free radicals, reactive oxygen species (ROS) and electrophiles produced during oxidative stress are capable of modifying nucleic acids, lipids and proteins. There are a variety of oxidative modifications...

Resource Type:

Dissertation

Full Text:

AN ABSTRACT OF THE DISSERTATION OF Juan D. Chavez for the degree of Doctor of Philosophy in