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Filtering by: Creator Jeroue, Lacey M. Remove constraint Creator: Jeroue, Lacey M. Committee Member Becker, Boris Remove constraint Committee Member: Becker, Boris Decade 1980-1989 Remove constraint Decade: 1980-1989

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  • New product formulation and multiple dose pharmacokinetics of acetaminophen

    Creator:
    Sahajwalla, Chandrahas G.
    Abstract:
    Four different treatments of acetaminophen were administered to eight healthy volunteers in multiple doses (five doses). Saliva acetaminophen concentration-time profiles were determined. Non-compartmental pharmacokinetic parameters for the first and last dose were calculated and compared to determine whether acetaminophen exhibited linear or dose dependent pharmacokinetics. Dose corrected area under the...
    Resource Type:
    Dissertation
    Full Text:
    ) Weight (Kg) Max Dose (mg/kg) 1 F 22 59.00 16.95 2 M 25 55.00 18.18 3 M 27 68.18 14.67 4 M 25 62.00