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Filtering by: Creator Watkins, Deane A. Remove constraint Creator: Watkins, Deane A. Committee Member Bermudez, Luiz Remove constraint Committee Member: Bermudez, Luiz

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  • Molecular basis for Clostridium perfringens spore resistance to heat and other environmental stress factors

    Creator:
    Raju, Deepa
    Abstract:
    Clostridium perfringens type A isolates producing enterotoxin (CPE) are an important cause of both food poisoning (FP) and non food borne gastrointestinal diseases (NFBGID) in both humans and animals. C. perfringens type A food poisoning is caused by isolates carrying the CPE encoding gene (cpe) on the chromosome while the...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Mahfuzur R. Sarker Clostridium perfringens type A isolates producing enterotoxin (CPE

  • Analysis of chlamydial and host proteins associated with infection

    Creator:
    Chu, Hencelyn
    Abstract:
    Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal host processes. Within host cells, their developmental cycle takes place inside non-acidified vacuoles termed inclusions. An inclusion membrane composed primarily of secreted chlamydial synthesized proteins called Incs encloses the inclusion. At this location, Incs have...
    Resource Type:
    Dissertation
    Full Text:
    Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal

  • Understanding chlamydial biology through genome sequencing and comparative genomics

    Creator:
    Jeffrey, Brendan
    Abstract:
    The human pathogen Chlamydia trachomatis displays different phenotypes between serovars both in vivo and in vitro. The study of chlamydial biology has been hampered by the lack of a tractable genetic system. Here, chlamydial isolates with known phenotypes as well as strains generated though recombination were fully sequenced to address...
    Resource Type:
    Dissertation
    Full Text:
    chlamydial biology has been hampered by the lack of a tractable genetic system. Here, chlamydial

  • Clostridium perfringens spores : inactivation, germination, and formation

    Creator:
    Udompijitkul, Pathima
    Abstract:
    The enterotoxin-producing Clostridium perfringens type A isolates are responsible for the third most common foodborne illness in the United States and can also cause non-foodborne human gastrointestinal (GI) diseases such as antibiotic- associated and sporadic diarrheas. Three important factors contribute to the ability of C. perfringens to cause GI diseases,...
    Resource Type:
    Dissertation
    Full Text:
    : __________________________________________________________________ Mahfuzur R. Sarker The enterotoxin-producing Clostridium perfringens type A isolates are

  • New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

    Creator:
    Banawas, Saeed S.
    Abstract:
    C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Mahfuzur R. Sarker C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic

  • Molecular mechanism of germination of Clostridium perfringens spores

    Creator:
    Paredes-Sabja, Daniel
    Abstract:
    Clostridium perfringens is the causative agent of a wide variety of diseases in animals and humans. C. perfringens can produce more than 15 toxins. However, individual strains produce a subset of these toxins. Although a small percentage of C. perfringens isolates (mostly belonging to type A) produce C. perfringens enterotoxin...
    Resource Type:
    Dissertation
    Full Text:
    a wide variety of diseases in animals and humans. C. perfringens can produce more than 15 toxins

  • Clostridium perfringens sporulation and gliding motility

    Creator:
    Huang, I-Hsiu
    Abstract:
    Clostridium perfringens type A isolates, an anaerobic enterotoxigenic spore forming bacterium, are the third leading cause of food-borne disease in the United States. Factors that contribute to the virulence of C. perfringens include the ability of the bacterium to form heat resistant spores and to produce an enterotoxin (CPE). Although...
    Resource Type:
    Dissertation
    Full Text:
    : ___________________________________________________ Mahfuzur R. Sarker Clostridium perfringens type A isolates, an anaerobic enterotoxigenic