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Filtering by: Subject Drug-nutrient interactions Committee Member Birkes, David

Alterations in the permeability of cimetidine by dietary flavonoids using an in vitro transport model, Caco-2 cell

Creator:

Taur, Jan-Shiang

Abstract:

The goal of this dissertation is to investigate the interaction between cimetidine and dietary flavonoids using the Caco-2 cell transport model. It has been shown that flavonoids can change the bioavailability of pharmaceuticals, either by inhibiting metabolizing enzymes or inhibiting the drug efflux transporters. However, the effect of dietary flavonoids...

Resource Type:

Dissertation

Full Text:

-drug Interaction.......................................4 2.2 Flavonoids