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Filtering by: Committee Member Birkes, David S. License All rights reserved

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

Creator:

Rakkanka, Vipaporn

Abstract:

This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...

Resource Type:

Dissertation
Propensity score adjustments using covariates in observational studies

Creator:

Yang, Daniel K.

Abstract:

In this thesis we develop a theoretical framework for the identification of situations where the equal frequency (EF) or equal variance (EV) subclassification may produce lower bias and/or variance of the estimator. We conduct simulation studies to examine the EF and EV approaches under different types of model misspecification. We...

Resource Type:

Dissertation