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Filtering by: Committee Member Blakemore, Paul R. Remove constraint Committee Member: Blakemore, Paul R. Committee Member Blakemore, Paul Remove constraint Committee Member: Blakemore, Paul Committee Member Anderson, Kim Remove constraint Committee Member: Anderson, Kim

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  • Improvements in synthesis and response techniques of ion-selective sensors

    Creator:
    Pylypiuk, Nataliia
    Abstract:
    Two improvements to the established procedures for synthesis and response detection of ion-selective optical sensors (optodes) were introduced. The first improvement addresses the drawback of organic dye (optode-localized chromoionophore) photobleaching. This positively impacts fluorescence response and allows for (1) direct measurement of hydrogen ion activity upon binding with the dye,...
    Resource Type:
    Masters Thesis
    Full Text:
    commitment of my graduate committee members: Kim Anderson, Paul Blakemore and Christopher Beaudry

  • A Pyrone Diels–Alder Approach to Substituted Indoles and Carbazoles and the Synthesis of New Ropinirole Analogues

    Creator:
    Points, Gary L., III
    Abstract:
    Aromatic heterocycles are core structural motifs in natural products, pharmaceuticals and biological polymers. Indoles, in particular, represent a significant subclass of aromatic heterocycles, both in terms of sheer numbers, but also in biological and pharmaceutical relevance. As such, new methodologies for the synthesis of indoles represent an important and continually...
    Resource Type:
    Dissertation
    Full Text:
    formation of a new carbon bond ortho to the R-substituent on the aryl ring is disfavored due to steric