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Filtering by: Creator Willoughby, Ryan Committee Member Blakemore, Paul

Gene Activation Strategies in Filamentous Fungi for Natural Products Discovery

Creator:

Adpressa, Donovon A.

Abstract:

Fungi have long been a prolific source of clinically approved drugs. The antibiotic penicillin, the cholesterol lowering statins, and the immunosuppressant cyclosporine have changed the treatment of human diseases in the last century. Recently, genome analysis of filamentous fungi has revealed that the biosynthetic potential for natural product expression is...

Resource Type:

Dissertation