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Filtering by: Contributor Gonzalez-Montiel, Gisela Remove constraint Contributor: Gonzalez-Montiel, Gisela Committee Member Blakemore, Paul R. Remove constraint Committee Member: Blakemore, Paul R.

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  • Bioprospecting the Chemical Diversity of Plant-associated Fungi

    Creator:
    González-Montiel, Gisela Abigail
    Abstract:
    Fungi have long been used for discovery of new chemical scaffolds. In the clinical setting, the fungal natural products penicillin, statins, and cyclosporine have revolutionized medicine to treat diseases and infections. In the environment, fungal natural products have been used as herbicides, fungicides, and insecticides to protect crops, livestock, and...
    Resource Type:
    Masters Thesis
    Full Text:
    . ©Copyright by Gisela A. González-Montiel July 11, 2019 All Rights Reserved Bioprospecting

  • Drug Discovery from Diverse Bacteria – Bioactivity-guided Isolation of Known and New Metabolites

    Creator:
    Zhu, Chenxi
    Abstract:
    Exploring bioactive natural products has contributed largely to clinically approved drugs we have been using over the last 100 years. Especially among the anti-infective drugs, around 70% of currently used antibiotics were discovered or derived from microbial secondary metabolites, among them compounds like vancomycin, chloramphenicol, and erythromycin. Facing the unavoidable...
    Resource Type:
    Dissertation
    Full Text:
    . Birte Plitzko, Gisela González- Montiel, Mahsa Khoshbakht, and many undergraduate students. I am