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Filtering by: Committee Member Borradaile, Glencora Creator Vogel, Amber J.

Strength in Numbers: How Multivalent WW-PPXY Interactions Regulate Cell Signaling

Creator:

Vogel, Amber J.

Abstract:

Cell signaling is often mediated by protein-protein interactions, which must be specific, tunable, and transient to allow agile responsiveness to cellular messages. Due to their unique properties, multivalent, intrinsically disordered proteins make ideal candidates to accomplish these vital tasks. A single protein with multiple binding sites may bind numerous partners,...

Resource Type:

Dissertation