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Filtering by: Creator Douillet, Philippe A. Remove constraint Creator: Douillet, Philippe A. Committee Member Borradaile, Glencora Remove constraint Committee Member: Borradaile, Glencora

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  • Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome

    Creator:
    Yao, Yao
    Abstract:
    We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...
    Resource Type:
    Dissertation
    Full Text:
    Ramsey We describe a series of novel computational models, CERENKOV (Computational Elu- cidation of the

  • Computational Approaches for RNA Structure Prediction with Dynamic Programming and Deep Neural Networks

    Creator:
    Deng, Dezhong
    Abstract:
    Our goal is to build a system to model the RNA sequences that reveals their structural information by using efficient dynamic programming algorithms and deep learning approaches. We aim to 1) achieve linear-time for RNA secondary structure prediction based on existing minimum free energy models; 2) utilize deep neural networks...
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: David A. Hendrix Our goal is to build a system to model the RNA sequences that reveals

  • Characterizing Server Compromise: Resilience Models, Instantiations, and Impossibilities

    Creator:
    McQuoid, Ian M.
    Abstract:
    One of the pervasive problems arising in our modern, digital world surrounds data breaches where an adversary, through zero-day exploitations, phishing, or old-fashioned social engineering attacks, gains access to a service’s data stores. Our society increasingly relies on these cloud-based services for everything from our taxes to personal communication. As...
    Resource Type:
    Dissertation
    Full Text:
    attacks, gains access to a service’s data stores. Our society increasingly relies on these cloud-based

  • Communication efficient private set and database operations

    Creator:
    Garimella, Gayathri Annapurna
    Abstract:
    Secure Computation is a powerful tool that enables a set of parties to jointly compute any function over their private inputs, without a trusted third party. Private Set Intersection is a specific case of two-party Secure Computation, where Alice (with private set X) and Bob (with private set Y) specifically...
    Resource Type:
    Dissertation
    Full Text:
    Secure Computation is a powerful tool that enables a set of parties to jointly compute any function over