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Filtering by: Creator Gregory, Sarah Committee Member Borradaile, Glencora

Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome

Creator:

Yao, Yao

Abstract:

We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...

Resource Type:

Dissertation
Improving User Mental Models of XAI Systems with Inclusive Design Approaches

Creator:

Hamid, Md Montaser

Abstract:

Explainable Artificial Intelligence (XAI) systems aim to improve users’ understanding of AI but rarely consider the inclusivity aspects of XAI. Without inclusive approaches, improving explanations might not work well for everyone. This study investigates leveraging users’ diverse problem-solving styles as an inclusive strategy to fix an XAI prototype, with the...

Resource Type:

Masters Thesis
Computational Approaches for RNA Structure Prediction with Dynamic Programming and Deep Neural Networks

Creator:

Deng, Dezhong

Abstract:

Our goal is to build a system to model the RNA sequences that reveals their structural information by using efficient dynamic programming algorithms and deep learning approaches. We aim to 1) achieve linear-time for RNA secondary structure prediction based on existing minimum free energy models; 2) utilize deep neural networks...

Resource Type:

Dissertation