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Filtering by: Creator Malin, Lucia Committee Member Borradaile, Glencora

Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome

Creator:

Yao, Yao

Abstract:

We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...

Resource Type:

Dissertation