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Filtering by: Committee Member Kimeldorf, Donald J. Committee Member Branscum, Adam J.

Regulation of Skeletal Muscle Mitophagy in Response to High-fat Feeding and Exercise Training

Creator:

Ehrlicher, Sarah E.

Abstract:

Understanding the mechanisms regulating mitochondrial respiratory function and adaptations to metabolic challenges, such as exercise and high dietary fat, is necessary to promote skeletal muscle health and attenuate metabolic disease. Autophagy is a constitutively active degradation pathway that promotes mitochondrial turnover and is suppressed by insulin and activated by exercise....

Resource Type:

Dissertation

Full Text:

Drs. Donald Jump, Viviana Perez and Adam Branscum, thank you for serving on my committee and for
The Relationship Between IGF-1 and Bone Turnover in a Non-Human Primate Model of Voluntary Alcohol Consumption

Creator:

Sattgast, Lara H.

Abstract:

Alcohol is a widely consumed, nonessential, bioactive nutrient with end-organ effects on the skeleton. Moderate levels of alcohol consumption are generally associated with increased bone mineral density (BMD), whereas higher intake levels result in reduced bone formation, bone loss, and increased risk for osteoporotic fracture. Given the negative impact of...

Resource Type:

Dissertation

Full Text:

committee members—Dr. Kathleen Grant, Dr. Adam Branscum, Dr. Donald Jump, and Dr. Maret Traber, for