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Filtering by: Creator Cunningham, Sam Committee Member Buermeyer, Andrew

The conserved biology of herpesvirus latency : a study in cyprinid herpesvirus 3

Creator:

Reed, Aimee N.

Abstract:

Cyprinid herpesvirus 3 (CyHV-3), commonly known as koi herpesvirus (KHV), is a member of the Alloherpesviridae and is a deadly pathogen for koi and common carp, Cyprinus carpio. It causes severe gill necrosis and nephritis, dermal ulceration and hemorrhage, and mass mortality of up to 100% of affected fish. Fish...

Resource Type:

Dissertation
Effect of PFAS Exposure on Reproduction : a Comparative Investigation between Kisspeptin-secreting AVPV and Arcuate Nuclei

Creator:

Jacobs, Dakota

Abstract:

Ovulation requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from preoptic hypothalamic neurons, initiated by elevated ovarian estradiol (E₂). Rising estradiol activates a subset of sexually dimorphic kisspeptin (Kiss-1) neurons in the female, located in the anteroventral periventricular nuclei (AVPV). Conversely, estradiol negative feedback on GnRH secretion is mediated by a...

Resource Type:

Masters Thesis
Functional analysis of novel β-catenin mutants

Creator:

Al-Fageeh, Mohamed B.

Abstract:

β-catenin is a multi functional protein that is involved in cell-cell adhesion and cell signaling. In non-stimulated cells, β-catenin is tightly down-regulated by GSK-3β-dependent phosphorylation at Ser and Thr residues, followed by rapid ubiquitination and proteasomal degradation. It is well established that mutations within the regulatory GSK-3β region lead to...

Resource Type:

Masters Thesis

Full Text:

binds to SAM? (Ser-Ala-Met-Pro) repeats in APC. This complex facilitates the phosphorylation and the