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Filtering by: Committee Member Chang, Jeff Remove constraint Committee Member: Chang, Jeff Subject Quorum sensing (Microbiology) Remove constraint Subject: Quorum sensing (Microbiology)

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  • Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

    Creator:
    Mellbye, Brett L.
    Abstract:
    Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...
    Resource Type:
    Dissertation

  • Quorum sensing gene regulation in Pseudomonas aeruginosa

    Creator:
    Gupta, Rashmi
    Abstract:
    Pseudomonas aeruginosa is an opportunistic human pathogen that infects immunocompromised individuals such as those suffering from burns or the genetic disorder cystic fibrosis. This organism utilizes a cell-cell communication mechanism known as quorum sensing (QS) to coordinate virulence gene expression and biofilm formation. It has three interconnected QS systems, namely...
    Resource Type:
    Dissertation

  • Evolution of a streamlined cooperator in Pseudomonas aeruginosa quorum sensing

    Creator:
    Huie, Jessica L.
    Abstract:
    Social behavior leading to the production of common goods is prone to exploitation. One such behavior in Pseudomonas aeruginosa is quorum sensing (QS), by which the bacteria produce signals to regulate extracellular common goods. Exploitation comes in the form of cheaters which have a mutation in the central quorum sensing...
    Resource Type:
    Masters Thesis

  • Cooperation and conflict in Pseudomonas aeruginosa quorum sensing

    Creator:
    Wilder, Cara N.
    Abstract:
    Pseudomonas aeruginosa is an environmental bacterium as well as an opportunistic pathogen that primarily infects immunocompromised individuals, including those suffering from cystic fibrosis. The density-dependent regulation of gene expression via cell-to-cell communication, also termed quorum sensing (QS), is an important virulence determinant in this organism. Generally, P. aeruginosa uses three...
    Resource Type:
    Dissertation