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Filtering by: Creator dos Santos, Miguel N. Remove constraint Creator: dos Santos, Miguel N. Committee Member Chang, Jeff Remove constraint Committee Member: Chang, Jeff

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  • Genetic Structure in Populations of the Douglas-fir Swiss Needle Cast Fungus Nothophaeocryptopus gaeumannii

    Creator:
    Bennett, Patrick I.
    Abstract:
    The fungus Nothophaeocryptopus gaeumannii is the causative agent of Swiss needle cast (SNC), a foliar disease of Douglas-fir. Disease is characterized by premature loss of foliage and reduced growth resulting from the inhibition of photosynthesis due to the occlusion of stomata by the ascocarps of N. gaeumannii. Although the disease...
    Resource Type:
    Dissertation
    Full Text:
    of stomata by the ascocarps of N. gaeumannii. Although the disease was first reported from Douglas

  • Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

    Creator:
    Asfahl, Kyle L.
    Abstract:
    Cell-cell communication in bacteria is understood to facilitate the coordination of population-wide cooperative behavior in the form of concerted gene expression. The opportunistic pathogen Pseudomonas aeruginosa uses such a communication mechanism to regulate a large group of genes important to virulence strategies in this bacterium. This general mechanism of communication...
    Resource Type:
    Dissertation
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    . aeruginosa, like many Gram-negative Proteobacteria, is mediated through the synthesis of diffusible N-acyl

  • Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

    Creator:
    Mellbye, Brett L.
    Abstract:
    Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...
    Resource Type:
    Dissertation
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    . aeruginosa QS is considered a cooperative behavior that can be exploited by lasR mutant cheaters that do

  • The Fitness Costs and Regulatory Strategies of Cooperative Siderophore Production in Pseudomonas

    Creator:
    Sexton, David
    Abstract:
    Cooperative behaviors in bacteria are increasingly appreciated for their relevance to microbial ecology and utility as model systems for social evolution. One example is the secretion of siderophores, a structurally diverse group of compounds that chelate extracellular iron. Siderophore production is considered cooperative because the benefits can be shared with...
    Resource Type:
    Dissertation
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    siderophores they do not produce, indicating that social conflict is ecologically relevant. However, many

  • Recombination, resistance, and drug discovery in Chlamydia

    Creator:
    Sandoz, Kelsi
    Abstract:
    The intracellular life cycle of Chlamydia has been difficult to study due to the inability to genetically manipulate the bacteria. As a result, indirect methods have been employed to study the pathogen and the aspects that contribute to its unique intracellular life cycle. A wide variety of laboratory adapted strains,...
    Resource Type:
    Dissertation
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    with different antibiotic resistant markers and pioneered the use of next gen sequencing to do full

  • Genetic dissection of Victoria blight disease susceptibility in Arabidopsis thaliana

    Creator:
    Sweat, Teresa A.
    Abstract:
    The fungus Cochliobolus victoriae causes Victoria blight of oats and Arabidopsis and is pathogenic due to its production of a compound called victorin, which induces programmed cell death in sensitive plants. Victorin sensitivity in Arabidopsis is conferred by the dominant gene LOCUS ORCHESTRATING VICTORIN EFFECTS1 (LOV1), which encodes a coiled-coil-nucleotide...
    Resource Type:
    Dissertation
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    the N-terminus of the protein (Meyers et al., 2003). In contrast, the rice genome encodes 480

  • A G-type Lectin Receptor-like Kinase Associated with Septoria Canker Resistance and Susceptibility Described using Multi-omics and Biotechnology

    Creator:
    Lenz, Ryan R.
    Abstract:
    Managers of forest and plantation ecosystems are encountering growing problems involving plant pathogens and the expanding geographic ranges of these pathogens. Historically unexposed stands are exceptionally vulnerable when a non-native pathogen is introduced because these pathogens can cause devastating disease in a host population that lacks co-evolved resistance mechanisms. One...
    Resource Type:
    Dissertation

  • Processing and functional diversity of plant microRNA

    Creator:
    Cuperus, Josh
    Abstract:
    RNA interference pathways can involve amplification of secondary siRNAs by RNA-dependent RNA polymerases. In plants, RDR6-dependent secondary siRNAs, including transacting siRNAs (tasiRNAs), arise from transcripts targeted by some microRNAs (miRNAs). In the case of TAS3 tasiRNA formation, ARGONAUTE7 (AGO7)-miR390 complexes interact with primary transcripts at two sites, resulting in recruitment...
    Resource Type:
    Dissertation
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    length. Twenty-one- nucleotide versions of miR173 and miR828 guide cleavage of target RNA, but do not