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  • Statistical analysis of RNA sequencing count data

    Creator:
    Mi, Gu
    Abstract:
    RNA-Sequencing (RNA-Seq) has rapidly become the de facto technique in transcriptome studies. However, established statistical methods for analyzing experimental and observational microarray studies need to be revised or completely re-invented to accommodate RNA-Seq data's unique characteristics. In this dissertation, we focus on statistical analyses performed at two particular stages in...
    Resource Type:
    Dissertation
    Full Text:
    throughout my entire Ph.D. study. Thank you Jeff for motivating my research on many interesting RNA-Seq

  • Inferring Patterns and Processes of Emergence in Clonal Phytophthora Epidemics using Population Genomic Approaches

    Creator:
    Cauldron, Nicholas C.
    Abstract:
    Oomycete and fungal pathogens threaten food, fiber, and forests around the world. With climate change, these pathogens are expected to emerge more frequently. Evolution can facilitate their emergence through mechanisms such as mutations that change or expand host range. Characterizing evolutionary mechanisms in plant pathogens will contribute to our ability...
    Resource Type:
    Dissertation
    Full Text:
    Presented June 6, 2023 Commencement June 2023 Doctor of Philosophy dissertation of Nicholas C

  • Origins and evolution of plant microRNA genes

    Creator:
    Fahlgren, Noah
    Abstract:
    Eukaryotic small RNA (~20-30 nucleotides) are diverse regulatory molecules that repress gene expression at the transcriptional and post-transcriptional levels, defend hosts against invading viruses and defend genomes against selfish DNA elements. Small RNA populations are studied by high-throughput sequencing of the total small RNA fraction isolated from cells, however, the...
    Resource Type:
    Dissertation
    Full Text:
    approved: James C. Carrington Eukaryotic small RNA (~20-30 nucleotides) are diverse regulatory