Index Catalog // ScholarsArchive@OSU

Creator:: Fan, Ying
Abstract:: This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
Resource Type:: Dissertation

Creator:: Hempel, Laura A.
Abstract:: Numerous studies have explored how alluvial channel size and morphology are adjusted to different sediment and flow conditions, yet we still know very little about how and to what degree the flow regime controls channel form and processes. We use the term ‘channel form’ to refer to the size and...
Resource Type:: Dissertation

Creator:: Sloat, Brian R.
Abstract:: Currently, the only anthrax vaccine licensed for human use in the United States is the Anthrax-vaccine-absorbed (AVA or Biothrax®). AVA suffers from several drawbacks, including a complicated and lengthy dosing schedule that requires six initial injections administered over eighteen months, followed by annual boosters. Therefore, a new generation anthrax vaccine...
Resource Type:: Dissertation

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