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Filtering by: Committee Member Conte, Frank Degree Field Biochemistry and Biophysics

Towards the understanding of the function of the histone "tails" with respect to the structure, stability, and function of chromatin

Creator:

Dong, Feng

Abstract:

By using immobilized trypsin, I have been able to prepare well-defined, stable trypsinized nucleosomes. The difficulties of lacking of control in the extent of trypsinization, which were encountered in previous studies with the use of free trypsin, have been eliminated. The nucleosomes and oligonucleosomes prepared by immobilized trypsin are suitable...

Resource Type:

Dissertation