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Filtering by: Committee Member Dashwood, Roderick Date issued sim 2006-12-13

Factors contributing to the formation of CC-->TT tandem mutations

Creator:

Skinner, Amy M.

Abstract:

The multistage model of carcinogenesis states that an accumulation of mutations in genes that are important for maintaining cellular homeostasis may lead to cancer. A specific type of mutation observed in particular types of cancer is the CC-->TT mutation found in the TP53 gene of patients with basal or squamous...

Resource Type:

Dissertation