Index Catalog // ScholarsArchive@OSU

Creator:: Yu, Zhen
Abstract:: Lymphomas and leukemias are the most common cancer in children and young adults and in utero exposure to carcinogens may contribute to the etiology of these cancers. A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), was administered to pregnant mice (15 mg/Kg b.w., gavage) on gestation day 17. Significant mortalities in...
Resource Type:: Dissertation
Full Text:: thank Dr. George S. Bailey, Dr. Roderick H. Dashwood, Dr. Ronald E. Wrolstad and Dr. Susan J. Tornquist

Creator:: Watson, Gregory
Abstract:: Sulforaphane is an isothiocyanate derived from cruciferous vegetables and has been under investigation as a cancer chemopreventive agent for over two decades. The compound is well tolerated and has been shown to slow cancer progression in several different pre-clinical models of carcinogenesis, such as of the lung, breast and colon....
Resource Type:: Dissertation
Full Text:: Palomera- Sanchez, Chelsea Black, Claudia S Maier, David E Williams, Roderick H Dashwood and Emily Ho

Creator:: Campbell, Yan
Abstract:: The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...
Resource Type:: Dissertation

Creator:: Hsu, Anna
Abstract:: Prostate cancer risk is significantly lower in Asian countries compared to the US, which has prompted interest in the chemo-preventative action of dietary components such as soy and green tea commonly found in Asian diets, such as soy and green tea. Studies have suggested that soy isoflavones and green tea...
Resource Type:: Dissertation
Full Text:: . Christiane Löhr conducted the pathological assessment of chapter 4, and Dr. Roderick Dashwood contributed

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