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Filtering by: Creator Tai, Chiew-Lan Remove constraint Creator: Tai, Chiew-Lan Committee Member David, Maude Remove constraint Committee Member: David, Maude Degree Level Bachelor's Remove constraint Degree Level: Bachelor's

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  • Position-Dependent Codon Usage Bias in the Human Transcriptome

    Creator:
    Subramanian, Kaavya
    Abstract:
    All life depends on the reliable translation of RNA to protein according to complex interactions between translation machinery and RNA sequence features. While ribosomal occupancy and codon frequencies vary across coding regions, well-established metrics for computing coding potential of RNA do not capture such positional dependence. Here, we investigate position-dependent...
    Resource Type:
    Honors College Thesis
    Full Text:
    occupancy and tRNA adaptation index (tAI). High PDCUB scores correspond to a tAI-defined translational