Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Baldwin, Carole C. Committee Member Deinzer, Max Creator Doneanu, Catalin E. Degree Field Chemistry

1. Mass spectrometric analysis of UV-crosslinked protein-nucleic acid complexes

Creator:: Doneanu, Catalin E.
Abstract:: The DNA-binding domains of E. coli uracil-DNA glycosylase (Ung) and human replication protein A (hRPA) were studied using a general protocol developed in our laboratory for probing protein-DNA interactions. The procedure involves purification and mass spectrometric analysis of the nucleopeptide-products of a tryptically digested UV-crosslinked protein-nucleic acid complex. In the...
Resource Type:: Dissertation
Full Text:: C-teminal). Additional experiments showed that at least one amino acid from the sequence 383-VSDF