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Filtering by: Creator Traber, Maret G. Remove constraint Creator: Traber, Maret G. Committee Member Estevez, Alvaro Remove constraint Committee Member: Estevez, Alvaro Degree Name Honors Bachelor of Science (H.B.S.) Remove constraint Degree Name: Honors Bachelor of Science (H.B.S.)

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  • The Effect of Protein Nitration on Cell Survival Pathways in Schwann Cells

    Creator:
    Graumann, Oliver W.
    Abstract:
    Neurofibromatosis type 2 (NF2) is a genetic disorder caused by the inactivation of the merlin tumor suppressor gene. NF2 patients develop bilateral vestibular schwannomas (VS) and other nervous system tumors with no effective drug treatment option. In pathological conditions, including NF2, production of the oxidant peroxynitrite leads to protein tyrosine...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Maret Traber, Committee Member, representing Biochemistry and Biophysics