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Filtering by: Has journal Environmental Science & Technology Committee Member Field, Jennifer Committee Member McGuire, Joseph

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Creator:

Joshi, Pranav R.

Abstract:

Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram-positive bacteria, was incorporated into novel block copolymer constructs and tested for retained antibacterial activity. Covalent coupling was achieved by chemical modification of the N-terminal isoleucine to introduce a thiol group. Thiolated nisin derivatives were then linked to poly[ethylene...

Resource Type:

Dissertation

Full Text:

to Dr. Tom Shellhammer at the Department of Food Science and Technology, for help with Zeta
Tandem mass spectrometric analysis of protein and peptide adducts of lipid peroxidation-derived aldehydes

Creator:

Wu, Jianyong

Abstract:

The adduction of proteins and other biomolecules by electrophilic lipid peroxidation products such as 4-hydroxy-2-nonenal (HNE), 4-oxo-2-nonenal (ONE), malondialdehyde (MDA) or acrolein (ACR) is thought to be an initiating and/or propagating factor in the pathophysiology of several diseases such as atherosclerosis, diabetes, Alzheimer's, Parkinson's and other age-related disorders. The identification...

Resource Type:

Dissertation
Rheological Techniques in Characterization and Aiding in the Modification of Soft Matter

Creator:

Daalkhaijav, Uranbileg

Abstract:

Soft matter encapsulates a large array of materials ranging from electronics, plastics, and cosmetics to the biofluids making up all organisms. One of the most important properties of these materials that dictate their functionality is their rheology, which is the flow and deformation behavior in response to stress. The focus...

Resource Type:

Dissertation

Full Text:

Engineering Head of the School of Chemical, Biological, and Environmental Engineering

ScholarsArchive@OSU

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Tandem mass spectrometric analysis of protein and peptide adducts of lipid peroxidation-derived aldehydes

Rheological Techniques in Characterization and Aiding in the Modification of Soft Matter

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