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  • Toward a flexible and accurate approach to null network sampling

    Creator:
    Bright, Zachary A.
    Abstract:
    Null networks are a type of random graph that is favored for the analysis of a wide variety of real-world networks, including gene-regulatory networks, food webs, and species co-occurrence matrices. As a hypothesis-generating tool, null networks are invaluable because they can reveal network motifs and unusual large-scale properties of networks...
    Resource Type:
    Masters Thesis
    Full Text:
    functional sub-units within a network. Within the context of biology, NMD can be applied to the analysis of

  • Computational Approaches for Understanding Combinatorial Gene Regulation

    Creator:
    Ansariola, Mitra
    Abstract:
    Gene regulation is a complex mechanism that controls the spatial and temporal expression of genes in a living cell. My dissertation studies focus on two problems. First, tissue-specific gene expression prediction from DNA sequence and chromatin state, and second, the accurate discovery of small over-represented regulatory circuits in gene regulatory...
    Resource Type:
    Dissertation
    Full Text:
    degree of Doctor of Philosophy in Molecular and Cellular Biology presented on January 5, 2018. Title