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Filtering by: Creator Sheley, R. L. Remove constraint Creator: Sheley, R. L. Committee Member Fowler, John Remove constraint Committee Member: Fowler, John Rights Statement In Copyright - Non-Commercial Use Permitted Remove constraint Rights Statement: In Copyright - Non-Commercial Use Permitted

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  • Computational Approaches for Understanding Combinatorial Gene Regulation

    Creator:
    Ansariola, Mitra
    Abstract:
    Gene regulation is a complex mechanism that controls the spatial and temporal expression of genes in a living cell. My dissertation studies focus on two problems. First, tissue-specific gene expression prediction from DNA sequence and chromatin state, and second, the accurate discovery of small over-represented regulatory circuits in gene regulatory...
    Resource Type:
    Dissertation
    Full Text:
    sequence R = C = {2, 1, 1, 2, 1, 1}. . . . 73 3.13 An illustrative view of graph sampling strategy

  • Toward a flexible and accurate approach to null network sampling

    Creator:
    Bright, Zachary A.
    Abstract:
    Null networks are a type of random graph that is favored for the analysis of a wide variety of real-world networks, including gene-regulatory networks, food webs, and species co-occurrence matrices. As a hypothesis-generating tool, null networks are invaluable because they can reveal network motifs and unusual large-scale properties of networks...
    Resource Type:
    Masters Thesis
    Full Text:
    = 1) = r, and 0 ≤ r ≤ 1 is a free parameter which determines the expected ratio of ones to zeros. A