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Filtering by: Creator Miller, Richard E. Remove constraint Creator: Miller, Richard E. Committee Member Franco, Maria C. Remove constraint Committee Member: Franco, Maria C. License Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND 4.0) Remove constraint License: Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND 4.0)

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  • Addressing ALS: Corroborating the Methodology of Studying the P2X7R Complex

    Creator:
    Veytsman, Edward Y.
    Abstract:
    Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in the motor cortex and spinal cord. Recent evidence suggests that the purine receptor P2X7 (P2X7R) plays a central role in the pathology of ALS. Previous research indicates that P2X7R activation by oxidatively modified heat shock protein 90...
    Resource Type:
    Honors College Thesis
    Full Text:
    patients' P2X7R complex. Key Words: P2X7 receptor, ALS, motor neurons, Hsp90 Corresponding e-mail