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  • The effect of a calcium channel blocker on exercise induced muscle damage and hemodynamic parameters in young, healthy adults

    Creator:
    Dvorak, Roman
    Abstract:
    Calcium channel blockers (CCB) was studied extensively in cardiology for their tissue protective effect following myocardial infarction; we hypothesized that administration of a CCB would interfere with the processes that result in exercise-induced muscle damage (EIMD) and delayed onset muscle soreness. To investigate the effects of a CCB on a...
    Resource Type:
    Dissertation
    Full Text:
    Franklin, Dr. Luana Beeson, and Dr. Anthony Wilcox for their help and patience throughout my program

  • Molecular mechanisms of peroxisome proliferator-activated receptor signaling

    Creator:
    Dowell, Paul T.
    Abstract:
    Peroxisome proliferator-activated receptors (PPARs) are members of a large group of ligand-regulated transcription factors that includes nuclear receptors for steroid and thyroid hormones, retinoids and vitamin D₃. Synthetic fibrates and thiazolidinediones that bind to and activate PPARs are used efficaciously in humans to remedy hypertriglyceridemia and non-insulin dependent diabetes mellitus,...
    Resource Type:
    Dissertation
    Full Text:
    Cellular Biology Director of Molecular n d Cell r Biology Program Dean of Grad fate School I