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Filtering by: Creator Sayavedra-Soto, Luis A. Committee Member Frei, Balz B.

Mitochondrial decay in the aging rat heart : changes in fatty acid-supported bioenergetics and macromolecular organization of the electron transport system

Creator:

Gómez Ramirez, Luis A.

Abstract:

Decline in cardiac pump function is a hallmark of aging where mitochondrial decay is an important underlying cause. Although certainly multifactorial in nature, both dysfunction of the machinery involved in the chemiosmotic process of energy transduction and lower capacity to maintain fatty acid-driven respiration are identified as intrinsic factors of...

Resource Type:

Dissertation

Full Text:

AN ABSTRACT OF THE DISSERTATION OF Luis A. Gómez for the degree of Doctor of Philosophy in