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Filtering by: Creator McGrath, Daniel Committee Member Freitag, Michael Decade 2010-2019

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Creator:

Goodale, Britton C.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...

Resource Type:

Dissertation

Full Text:

thank others at OSU for their support; I am grateful to my committee members Daniel Sudakin, Michael
Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Creator:

Kimbrel, Jeffrey A.

Abstract:

Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...

Resource Type:

Dissertation