Index Catalog // ScholarsArchive@OSU

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Creator:: Ding, Jun
Abstract:: The studies described in this thesis were motivated by ongoing efforts to develop lignocellulosic biomass as an efficient and practical source of renewable energy. Enormous problems complicate these efforts to reduce reliance on greenhouse gas-generating fossil fuels. Simply obtaining the fermentable sugars available in the cellulose and hemicellulose components of...
Resource Type:: Dissertation
Full Text:: Freitag, and Dr. Fred Stevens for their advice and help towards the completion of my program. Many

Roles of homeodomain transcription factors during organogenesis

Creator:: Xu, Jun
Abstract:: The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
Resource Type:: Dissertation
Full Text:: . Nature 401:276-278. McGinnis W, Levine MS, Hafen E, Kuroiwa A, Gehring WJ (1984) A conserved DNA

Effects of biocide treatment on durability and fungal colonization of teak, western redcedar, and redwood

Creator:: Cabrera Orozco, Yohanna
Abstract:: Treating durable, second-growth or plantation-grown material with supplemental chemicals could improve durability while enhancing the uniformity of the products. To test this hypothesis, the effect of two candidate biocide treatments on the durability of teak, redwood, and western redcedar was assessed in a ground proximity field test established in Hawaii....
Resource Type:: Dissertation
Full Text:: Ecuador ............................................... 45 3.2. A ground proximity test AWPA E-18

Functional and Structural Analyses of Three Distinct proteins by Biochemical and Biophysical Techniques

Creator:: Codding, Sara Jone
Abstract:: The focus of this dissertation was to understand protein function and structure ona molecular level. To do this successfully, a variety of biochemical and biophysicaltechniques were employed. A wide variety of techniques were applied to study theproteins of interest in this dissertation to probe protein-protein interactions, proteinfunction, protein structure, and...
Resource Type:: Dissertation

Effects of DNA mismatch repair inhibition in Arabidopsis thaliana

Creator:: Wilcox, Buck W. L.
Abstract:: Genomic instability underlies diseases of unregulated cell growth that result in cancers and developmental abnormalities in humans. Similar genome destabilizing mechanisms are used to create genetic variety in crops for use in breeding and trait development. Errors that occur during DNA replication may cause mutations if they are not corrected...
Resource Type:: Dissertation
Full Text:: varying and complementary lesion substrate specificities and cell cycle-specific regulation. In E

Unraveling the endogenous functions of the aryl hydrocarbon receptor (AHR) and characterizing a novel long non-coding RNA (slincR) that contributes to AHR-mediated toxic responses in zebrafish

Creator:: Garcia, Gloria R.
Abstract:: The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that is a member of the basic helix-loop-helix PER-ARNT-SIM (bHLH/PAS) protein family of cellular sensors. The AHR is conserved across multiple animal phyla and is required for proper vertebrate development. A structurally diverse group of chemicals, including polycyclic aromatic...
Resource Type:: Dissertation
Full Text:: E. Peterson Lab from the University of Wisconsin-Madison, Madison, WI, USA. Abraham Garcia

Prostate cancer prevention with broccoli : from cellular to human studies

Creator:: Clarke, John D.
Abstract:: Prostate cancer is the second leading cause of cancer related death in American men. Epidemiologic studies suggest that cruciferous vegetable intake may lower the risk for many cancers, including prostate and colon. Isothiocyanates (ITC) are phytochemicals derived from cruciferous vegetables such as broccoli, Brussels sprouts, cauliflower, and cabbage that may...
Resource Type:: Dissertation

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Creator:: Kimbrel, Jeffrey A.
Abstract:: Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Resource Type:: Dissertation

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

Creator:: Manchanda, Aayushi
Abstract:: Otoferlin is a C2-domain, transmembrane protein whose mutated form is responsible for the DFNB9 subtype of prelingual hearing impairment. Mutations in otoferlin cause an autosomal recessive, non-syndromic form of deafness that is characterized by auditory neuropathy/ auditory dissynchrony (AN/AD), meaning that the outer hair cells (OHCs) are normal, and the...
Resource Type:: Dissertation

ScholarsArchive@OSU

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Roles of homeodomain transcription factors during organogenesis

Effects of biocide treatment on durability and fungal colonization of teak, western redcedar, and redwood

Functional and Structural Analyses of Three Distinct proteins by Biochemical and Biophysical Techniques

Effects of DNA mismatch repair inhibition in Arabidopsis thaliana

Unraveling the endogenous functions of the aryl hydrocarbon receptor (AHR) and characterizing a novel long non-coding RNA (slincR) that contributes to AHR-mediated toxic responses in zebrafish

Prostate cancer prevention with broccoli : from cellular to human studies

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

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