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Filtering by: Creator Bredeweg, Erin L. Remove constraint Creator: Bredeweg, Erin L. Committee Member Freitag, Michael Remove constraint Committee Member: Freitag, Michael Non-Academic Affiliation Oregon State University. Graduate School Remove constraint Non-Academic Affiliation: Oregon State University. Graduate School

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  • Effects of DNA mismatch repair inhibition in Arabidopsis thaliana

    Creator:
    Wilcox, Buck W. L.
    Abstract:
    Genomic instability underlies diseases of unregulated cell growth that result in cancers and developmental abnormalities in humans. Similar genome destabilizing mechanisms are used to create genetic variety in crops for use in breeding and trait development. Errors that occur during DNA replication may cause mutations if they are not corrected...
    Resource Type:
    Dissertation
    Full Text:
    , Sanjuro Jogdeo, Erin Bredeweg, and Kyle Pomraning for their invaluable advice and patience in helping me

  • Chemopreventative and chemotherapeutic properties of whole cruciferous vegetables and phytochemical components in acute T-cell lymphoblastic leukemia/lymphoma

    Creator:
    Shorey, Lyndsey E.
    Abstract:
    Acute lymphoblastic leukemia (ALL) encompasses a spectrum of lymphoid progenitors that have undergone malignant transformation and clonal proliferation at various stages of differentiation. Some cases of ALL have been documented to have prenatal origins and in particular neonatal exposure to various environmental pollutants is associated with increased disease risk, including...
    Resource Type:
    Dissertation
    Full Text:
    interpretation, and manuscript preparation. LS carried out the study and prepared the manuscript. Erin

  • Functional and Structural Analyses of Three Distinct proteins by Biochemical and Biophysical Techniques

    Creator:
    Codding, Sara Jone
    Abstract:
    The focus of this dissertation was to understand protein function and structure ona molecular level. To do this successfully, a variety of biochemical and biophysicaltechniques were employed. A wide variety of techniques were applied to study theproteins of interest in this dissertation to probe protein-protein interactions, proteinfunction, protein structure, and...
    Resource Type:
    Dissertation
    Full Text:
    . Johnson for their financial support. Lastly, and most importantly, I would like to thank Erin, who was

  • Transcriptomic analysis using high-throughput sequencing and DNA microarrays

    Creator:
    Fox, Samuel E.
    Abstract:
    Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...
    Resource Type:
    Dissertation
    Full Text:
    my father Ron and my mother-in-law, Terry. Finally, special thanks to my lovely wife Erin, mother